Of note, 479 transcripts were specially decreased in TB cells and enriched in metabolic process, including CYP3A4, CYP3A5, CYP2C19, CYP2C9, CYP2C18, CYP2C8, which might be inhibited in the presence of pro‐inflammatory cytokines (such as IL‐6, TNF‐α, TGF‐β, and IFN‐γ).[11] Consistent with previous studies,[1, 3, 4, 6] we also observed that 460 transcripts in cluster 14 were specially increased in TB cells and enriched in extracellular matrix organization and p‐EMT, including LAMA3, LAMB3, LUM, COL3A1, TGFB3, MMP2, COL12A1, FN1, MMP12, ITGA5, COL1A2, VCAN, and COL1A1. This evidence concerns the gene LAMB3 and tuberculosis.