Programmed cell death protein 1 (PD‐1) inhibitors were the most frequent type of ICI reported to be associated with SJS/TEN, followed by the combination of PD‐1 and cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) inhibitors, and PD‐L1 inhibitors (Figure 1d). This evidence concerns the gene CD274 and toxic epidermal necrolysis.