The PG lesion of PASH syndrome patients shows significantly elevated levels of inflammatory cytokines and mediators, including IL‐1β, TNF‐α, IL‐17, IL‐8, MMP‐2, and MMP‐9, compared to healthy skin.19, 83. Here, IL17A is linked to Pyoderma gangrenosum-acne-suppurative hidradenitis syndrome.