IL1R1 and obesity disorder: For example, an animal study which examined the impact of ablation of IL‐1 receptor 1 (IL‐1R1), in conjunction with diet‐induced obesity during pregnancy showed that not only was there no benefit for the IL‐1R1−/− mice, but their metabolic health worsened both during pregnancy and the postpartum period compared to their wild‐type counterparts (Plows et al., 2021).