LEP and systemic lupus erythematosus: SLE mice have higher body weight (Figure 1A, Control: 34.4 ± 0.5 vs. SLE: 43.4 ± 0.7 g, P<0.0001) and elevated circulating leptin levels (Figure 1B Control: 10.6 ± 1.3 vs. SLE: 25.5 ± 4.6 ng/ml, P=0.0078) compared with control mice at 28 weeks of age, in agreement with previously published data [28].