SCD and posterior cortical atrophy: First, support for our study comes from previous reports, in which taurine is shown to be capable to bind to LXRα during the process of lipogenesis in hepatocytes[20] and LXRα activates the transcription of SCD1 in human preadipocytes.[35] Rather than in lipogenesis, our study reveals that taurine can activate LXRα and upregulate the expression of SCD1 during the resistance to ferroptosis in PCa.