AKT1 and cancer: As shown in Fig. 4A, B, the top 10 items were identified based on the KEGG analysis with p-values < 0.05, mainly included MAPK signaling pathway, PI3K-AKT signaling pathway, Rap1 signaling pathway, progesterone-mediated oocyte maturation, central carbon metabolism in cancer, endocrine resistance, acute myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, regulation of lipolysis in adipocytes, and VEGF signaling pathway.