IL6 and atherosclerosis: Trichostatin A (TSA), another specific HDACi, exacerbates atherosclerosis via increasing acetylation at the scavenger receptor CD36 promoter region, tumor necrosis factor (TNF)-alpha, and vascular cell adhesion molecule-1 (VCAM-1) and decreasing IL-6 and IL-1beta expressions in Ldlr−/− mice [125, 126].