TSPOAP1 and obesity due to melanocortin 4 receptor deficiency: Moreover, findings from overweight/obese Korean subjects suggest an association between DNA hypermethylation at the TSPO-associated protein 1 antisense RNA 1 (TSPOAP1-AS1) promoter and overweight/obesity, as well as significant positive correlations between LDL cholesterol levels and TSPOAP1-AS1 DNA hypermethylation levels [36].