While in immune-stromal cells of the tumor (Table 3), ASA classification (x2=6.186, P=0.045) was found closely related to NLRP3 expression, and histological grades (Fisher test, P=0.001) were found closely related to IL-18 expression; and the proportion of high expression of ASC in the stroma of breast cancer in TNBC patients was significantly higher than that in non TNBC patients (Fisher test, P=0.015). The gene discussed is IL18; the disease is neoplasm.