Moreover, there was an evident trend that naïve CD4 T cells (P = 0.051) and follicular helper T cells (P = 0.050) were more abundant in NTRK3 MT NSCLC, while the infiltration of Tregs (P = 0.009) was more enriched in NTRK3 WT NSCLC (Fig. 5D). Here, CD4 is linked to non-small cell lung carcinoma.