Regarding NTRK2, most immune checkpoint signatures (CD274, CTLA4, IDO1, PDCD1LG2, LAG3, TIGIT, PDCD1, and HAVCR2) were mildly lower in NTRK MT NSCLC than in NTRK WT NSCLC (Fig. 5G). The gene discussed is HAVCR2; the disease is non-small cell lung carcinoma.