We generated xenografts for WT A375 and A3 and A10 CDC20 promoter indel melanoma cell lines (5 mice per cell line, 2 flank tumors per mouse, 3 cell lines for a total of 30 total tumors) and measured tumor volume over the course of 6 weeks with unblinding only after completion of all measurements and analysis (Fig. 5d, Supplemental Data 11). The gene discussed is CDC20; the disease is neoplasm.