Thus, the selective deletion of IL-5+ ILC2s in the R5: Gata3f/f mice, or the conditional ablation of Tslp from dermal TRMs in the Ccl24-cre: Tslpf/f mice, in each case resulted in decreased numbers of ILC2s, eosinophils and dermal TRMs in the lesions, and ameliorated the infection outcome. The gene discussed is CCL24; the disease is infection.