HEXB and infection: Since an intensified inflammatory state is marked by an increase in the activity of lysosomal exo-glycosidases in tissues and body fluids, especially the most active HexB (Chojnowska et al., 2018), we propose a hypothesis that the combination of CA-MRSA pathogen and GSLs activates HexB with the local inflammatory response to breast abscesses, which is critical for GSLs synthesis and mediates the specific infection process caused by CA-MRSA.