CISH and infection: Infection led to a significant increase in the frequency of all erythroblast populations and a decrease in RBC in both genotypes, but basophilic, polychromatic and orthochromatic erythroblasts all increased to a greater extent in Cish−/− mice such that they were significantly higher than in Cish+/+ mice at 8 dpi (Figure 4C; Supplementary Figure S1).