Comparative analysis of gene expression revealed that ACE2 and FURIN, which are genes significantly associated with SARS-CoV-2 infection, are upregulated in psoriasis patients, and 48 of 161 genes that are upregulated in the lungs of COVID-19 patients are also positively regulated in psoriasis (Singh et al., 2021). Here, ACE2 is linked to COVID-19.