The evolutionary conserved small nucleolar host gene 12 (SNHG12) was found to be decreased in aortic ECs in atherosclerotic lesions.44 The same group then investigated its role in angiogenesis and PAD and found that SNHG12 was decreased in ischemic ECs and increased with perfusion recovery. This evidence concerns the gene SNHG12 and Atherosclerotic lesion.