PLAUR and type 2 diabetes mellitus: These molecules are glycoproteins and found in most tissues and body fluids.9 The uPA–uPAR system is not only complicated in fibrinolysis, but it also controls cell proliferation, angiogenesis, adhesion and enrollment of inflammatory cells.10 Recently, suPAR has increased concern as a potential risk marker for T2DM, CVD, cancer and mortality in the widely populace.11 Higher serum suPAR levels have also been related with subclinical organ damage and CV complications, assisting to expect mortality causes in ischemic stroke.12