IL6 and coronary artery disorder: The NFKB1 gene increased the expression of pro-inflammatory cytokines.29 The NFKB1-94ins/del ATTG polymorphism caused elevated IL-6 levels, suggesting a mechanistic link between rs28362491 and CAD susceptibility.30 However, this study found no association between the NFKB1-94ins/del ATTG polymorphism and the Gensini and Syntax scores.