A study reported a significant association of NF-κB1 -94ins/del ATTG polymorphism with the risk of diabetes and diabetes-related dyslipidemia in the dominant and heterozygous genetic models.9 Fakhir et al found no significant association between NFKB1-94 ins/del ATTG genotypes and levels of AST and ALT.32 Yongchao et al conducted a case-control study to assess the association of genotype rs28362491 with hepatocellular carcinoma development in HBV-infected patients. The gene discussed is NFKB1; the disease is metabolic syndrome.