CD4 and Sepsis: Figure 7A displays the proportions of 22 immune cell types in samples from the sepsis group and the normal group. The box plots demonstrate that sepsis patients have higher levels of Macrophages M0, Macrophages M2, Mast cells resting, and Mast cells activated, while lower levels of T-cells CD8+, T-cells CD4 naive, CD4 memory resting, and T-cells follicular helper (Figure 7B). Furthermore, we observed significant correlations between the five hub genes and immune cell infiltration in sepsis, as depicted in Figure 7C.