This study’s observations cannot be further corroborated without accounting for other factors heavily intertwined with the sex, such as the familial history of T1D, the presence of high-risk SNPs (e.g., INS and PTPN22), and especially the viral background which we postulate to be the main environmental risk factor interacting with the CXADR. The gene discussed is INS; the disease is type 1 diabetes mellitus.