CXADR and type 1 diabetes mellitus: Lastly, in the context of disease pathology, enhanced expression of CXADRs has been observed in the pancreatic cells of individuals with T1D (Hodik et al., 2016), and a range of CXADR SNPs are associated with myocardial infarction (Marsman et al., 2011) and lung cancer (Li et al., 2022).