eIF4A1 is dysregulated and aberrantly expressed in many different tumor tissues (LIN et al., 2018), although the exact role of eIF4A1 in tumorigenesis and development is unclear, it may be associated with abnormal RNA unwinds function and lead to aberrant expression of proteins formed by aberrant RNA translation (LOH et al., 2009). This evidence concerns the gene EIF4A1 and neoplasm.