As an important component of eIF4F, eIF4A1 plays an important role in the process of gastric carcinogenesis and development and epithelial mesenchymal transition in gastric cancer, and recent studies have shown that the expression of eIF4A1 in cancers such as gastric cancer, colorectal cancer, cervical cancer, breast cancer, and melanoma exhibits abnormalities (LIANG et al., 2014; MODELSKA et al., 2015; JOYCE et al., 2017; GAO et al., 2020; CHEN et al., 2021a; SOYLEMEZ et al., 2021). Here, EIF4A1 is linked to melanoma.