EIF4A1 and colorectal cancer: However, Zafer et al. found that eIF4A1 was highly expressed in stage II colorectal cancer tissues and lowly expressed in stage I, III, and IV colorectal cancer tissues, and that eIF4A1 was highly expressed in the peripheral blood of patients with stage I, II, and III colorectal cancer, but lowly expressed in patients with stage IV colorectal cancer (SOYLEMEZ et al., 2021).