Combined inhibition of the Raf/MAPK/extracellular signaling-regulated kinase axis and eIF4A1 decreased the 5′-capsule-dependent translational process and attenuated the growth, metastasis, and invasiveness of cutaneous squamous cell carcinoma cells (ZHAO et al., 2019; SRIVASTAVA et al., 2021). This evidence concerns the gene EIF4A1 and cutaneous squamous cell carcinoma.