Similarly, Zhao et al. found that in Myc-amplified G3-type medulloblastoma (G3-MB), eIF4A1 was highly expressed and positively correlated with Myc expression, and that inhibiting eIF4A1 expression could effectively inhibit Myc expression at the translational level, and through this process, promote apoptosis of G3-MB cells and inhibit G3-MG cell proliferation to block the growth of tumor cells (ZHAO et al., 2020). Here, EIF4A1 is linked to neoplasm.