Then, analyzing the results of the identified compounds from metabolomics to routine laboratory parameters of the clinical course in patients with ALMS and BBS, strong correlations between selected phospholipids and parameters of glucose metabolism such as: HbA1c (indicator of chronic hyperglycaemia), HOMA-IR (marker of insulin resistance) and C-peptide levels (marker of insulin secretion) were observed (Table 2). This evidence concerns the gene INS and Hyperglycemia.