For instance, GATA4, identified as an ACC biomarker, is thought to influence proliferation by regulating transcription in several cancer types (Zheng and Blobel, 2010); KCNJ14 is a biomarker for cancer progression and development (Alasiri, 2023); overexpression of the small nucleolar RNA SNORD1143 was observed in AML and Acute Promyelocytic Leukemia (APL) (Liuksiala et al., 2014). This evidence concerns the gene GATA4 and acute myeloid leukemia.