AKT1 and axial length measurement: PIs are precursors of phosphoinositide, such as PI(3,4,5)P3, which can promote tumorigenesis by activating the AKT/mTORC1/2 pathway, which is frequently altered in AL (Nepstad et al., 2020), while SF participates in regular signals of cell survival or apoptosis (Ogretmen, 2018).