Moreover, compared with the patients without CA-AKI, patients in the CA-AKI group had worse renal function (Scr increased proportion: 2.50% [−4.60 to 10.60] vs. 39.10% [30.50 to 59.60], P < 0.001), worse cardiac status (NT-proBNP: 358.0 [102.0 to 1108.5] vs. 1475.0 [401.5 to 3440.0] μg/ml, P < 0.001), higher inflammatory level (CRP: 1.70 mg/L [0.80 to 5.10] vs. 3.50 mg/L [1.20 to 11.20], P < 0.001), higher prevalence of diabetes (22.8% vs. 28.4%, P = 0.01), and less frequent usage of statin (83.7% vs. 78.9%, P = 0.01). This evidence concerns the gene NPPB and acute kidney injury.