METTL3 and neoplasm: It can be seen from Fig. 2A that the differentially expressed m6A-regulated genes METTL3, METTL5, ZCCHC4, YTHDF1, HNRNPC, LRPPRC, HNRNPA2B1, IGF2BP1, IGF2BP3, TRMT112 and CPSF6 are highly expressed in tumor samples; genes METTL14, METTL16, WTAP, ZC3H13, PCIF1, SETD2, FTO and ALKBH3 were lowly expressed in tumor samples.