For the Ischemic Stroke dataset, as presented in the Supplementary Fig. 2 graph, the most significant contributing transcripts were: KRT15 (Keratin 15), VPRBP (Viral protein R binding protein), TNFRSF4 (TNF receptor superfamily member 4), GORASP2 (Golgi reassembly stacking protein 2). This evidence concerns the gene TNFRSF4 and ischemic stroke.