The beneficial role of enoxolone in Alzheimer's disease has also been suggested by inhibiting presenilin stabilization factor like protein (PSFL) which plays vital role in beta amyloid plaques formation [46].Overall, the phytocompound with anticholinesterase potential present in DEMG might be modulating the cholinergic system in the brain, resulting in increased learning and memory noted in DEMG-treated mice in Y-maze, PAT, and MWM tests. The gene discussed is APH1B; the disease is early-onset autosomal dominant Alzheimer disease.