IL6 and Sepsis: Six studies reported detection outcomes of IL-6 in the detection of sepsis, the pooled sensitivity was 0.81 (95% CI: 0.73, 0.87; I2 = 68.8%, p = 0.007) and the pooled specificity was 0.77 (95% CI: 0.72, 0.81; I2 = 87.5%, p < 0.001), respectively.