Two studies reported outcomes of IL-8 in the detection of sepsis, the pooled sensitivity was 1.00 (95% CI: 0.94, 1.00; I2 = NA, p = NA) and the pooled specificity was 0.05 (95% CI: 0.01, 0.18; I2 = NA%, p = NA), respectively. This evidence concerns the gene CXCL8 and Sepsis.