DPAGT1 and autosomal dominant polycystic kidney disease: Furthermore, the authors were the first to examine uAGT/Cr as a prognostic biomarker in ADPKD and found that, indeed, the uAGT/Cr ratio correlates positively with the risk of all-cause mortality and renal function decline in ADPKD patients, proposing its utility as a prognostic biomarker in ADPKD patients.