ABCA1 and ataxia telangiectasia: While ABCA1 variant c.2602G>A was associated with improved insulin sensitivity in AAs in our cohort, the c.2089G>A variant was associated with increased visceral AT, and c.634T>A, identified only in a subgroup of Hispanic youth, was associated with elevated small LDL cholesterol levels, exemplifying the messy interplay of genetic variation.