PPARG and obesity due to melanocortin 4 receptor deficiency: In a cohort of Northwest Mexican adults, single-nucleotide polymorphisms (SNPs) in the ABCA1 gene as well as FTO alpha-ketoglutarate-dependent dioxygenase (FTO), adrenoceptor beta 3 (ADRB3), and PPARG were associated with increased risk of obesity (37).