Emphasizing the fact that early diagnosis can lead to higher chances of therapeutic success, utilizing the role of low-density lipoprotein receptor 1 (LOX-1) as a potential biomarker, anti-LOX-1 superparamagnetic iron oxide PEG-coated nanoparticles have been designed to identify inflammatory renal lesions during early stages of DN (51). Here, OLR1 is linked to liver dysplastic nodule.