No significant differences were observed in the general characteristics (such as age, sex ratio, weight, BMI, waist circumference, waist-to-hip ratio, and duration of diabetes) and efficacy and safety indicators (including CHOL, TG, HDL,LDL, FBG, HbA1c, HOMA-IR (CP), ALT, AST, Cr, UA, OGTT AUC (h·mmol/L), and insulin dose)between the three groups (P >0.05; Table 1). The gene discussed is GPT; the disease is diabetes mellitus.