PTPRC and type 1 diabetes mellitus: With an average of 0.3 ± 0.03 CD45+ cells per islet, islet lymphocytic infiltration in all donor pancreases of this study (including the donor with the exceptional high number of viruses; Figure 2) was much lower than the defined threshold of 15 CD45+ cells/islet for T1D (58, 59), which confirms classification to T2D of cases analyzed in this study, despite the higher number of inner-islet-CD45+ cells in T2D, compared to nondiabetic controls.