NFKB2 and autoimmune polyendocrine syndrome type 1: Informative syndromes caused by errors in essential immune genes like AIRE (autoimmune polyendocrine syndrome type 1, APS-1) and NFKB2 (DAVID syndrome) causing autoimmune disease in the adrenals either as a primary or secondary, further throw light on parts of the pathogenesis of autoimmune PAI.