GH2h correlated with all parameters of biochemical control at 6 months of follow-up: GH (rs 0.51; p=0.001), IGF1-SDS (rs 0.43; p<0.01), and tumor volume (rs 0.74; p<0.001); and with the %ΔIGF1 (rs 0.36; p=0.01), the ΔGH% (rs 0.50; p<0.01), and the Δvolume% (rs 0.49; p=0.02) (Figure 2). The gene discussed is IGF1; the disease is neoplasm.