Long non-coding RNA H19 from the exosomes of M2 tumor-associated macrophages inhibits the interaction between ULK1 and its specific E3 ubiquitin ligase NEDD4L, stabilizing ULK1 expression and promoting autophagy in bladder cancer cells (Guo Y. et al., 2022). This evidence concerns the gene NEDD4L and urinary bladder carcinoma.