ABCG2 and Thrombocytopenia: For example, rs2231142 in the ABCG2 mutant-type (A/A) is significantly associated with sunitinib-induced severe thrombocytopenia (Low et al., 2016), whereas rs2622604 in the ABCG2 mutant-type (T/T) is significantly associated with irinotecan-induced severe myelosuppression (Cha et al., 2009).