On the other hand, various investigators have also reported increased sensitization of tumor cells to radiotherapy through EGFR inhibition in head and neck squamous cell carcinoma (SCC), human colon cancer (GEO), colon cancer, ovarian (OVCAR-3), glioblastoma multiple (Huang et al., 1999; Bianco et al., 2000; Huang and Harari, 2000; Wang et al., 2020a). This evidence concerns the gene EGFR and colonic neoplasm.