BAX and colorectal cancer: Also, RSV has been shown to suppress the growth of HCT116 colorectal cancer cells by inhibiting SIRT1-dependent NF-ĸB, in addition to inducing apoptosis in ls174t cells through the induction of the expression of the proapoptotic protein Bax inhibits the anti-apoptotic protein Bcl-2 (B-cell lymphoma 2) (Chen et al., 2009; Buhrmann et al., 2016).