NFKB1 and cancer: NF-κB is activated by different molecules and signaling pathways, and in turn, this transcription factor modulates the expression of several genes (more than 500 genes) that participate in inflammatory responses, cell differentiation, adaptation to stress, apoptosis, immunity, and one of the main effector pathways that regulate the amount of ROS that leads to cell survival and at the same time to chemoresistance in cancer (Morgan and Liu, 2011; Vinod et al., 2013).