ERBB2 and breast cancer: Interestingly, RSV treatment inhibits HER-2 activation through docetaxel-induced blockade of MAPK and Akt signaling, as well as survival signaling pathways activated by HER-2, enhancing the sensitization of breast cancer cells (SK-BR-3 and MDA-MB-231) to docetaxel (Vinod et al., 2015).