The Cancer Genome Atlas (TCGA) data showed that the expression of ELA gene (APELA) was upregulated in the colon, lung, gastric, and thymoma cancers; however, APELA was systematically downregulated in all kidney cancer types, including renal chromocytocarcinoma, papillary kidney cancer, and clear cell renal cell carcinoma.Moreover, APELA is negatively correlated with the expression of the cell proliferation marker Ki-67 in the above kidney cancer. This evidence concerns the gene APELA and clear cell renal carcinoma.