FAP and neoplasm: Figures 4B, C show that [68Ga]Ga-FAP-2286-ICG were highly uptake by the tumor at 30 min after injection. Furthermore, SUVmax of the tumor was 0.57 ± 0.10 at 30 min, 0.51 ± 0.11 at 60 min, and 0.58 ± 0.23 at 90 min, indicating constant uptake of [68Ga]Ga-FAP-2286-ICG in the tumor. Other organs demonstrated low nonspecific binding that gradually decreased, resulting in low background signal and favorable tumor-to-background ratios (Figure 4D).