PWH with large VAT areas had higher odds of low NT-proBNP when adjusting for age, sex, smoking, diabetes, hypertension, eGFR, HCV antibodies, and BMI (aOR 1.69 [1.09–2.62], p=0.02), but the association was attenuated when further adjusting for LAVi (aOR 1.58 [0.95–2.62], p=0.08) (Table 2). This evidence concerns the gene NPPB and Hypertension.