ACE2 and Venous thrombosis: According to this systematic review and exploratory analysis study, the pathophysiology behind venous thrombosis is explained as follows: “New experimental studies have assumed that thrombosis is related to a soluble adenoviral protein spike variant, originating from splicing events, which cause important endothelial inflammatory events, and binding to endothelial cells expressing ACE2” (16) (p.2).