ADAM8 is expressed as an antigen of tyrosine kinase inhibitor-resistant chronic myeloid leukemia cells in a model of chronic myeloid leukemia stem cells produced from chronic myeloid leukemia-induced pluripotent stem cells (Miyauchi et al., 2018). The gene discussed is ADAM8; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.