FTH1 and Lymphatic Metastasis: FTH1 expression has prognostic value of OS (both P < 0.05) and DFS (both P < 0.05) whether lymphatic metastasis or not (Figs. 5C and 5D, Figs. 6C and 6D); FTH1 expression has a predictive value of DFS (P = 0.002) but no predictive value of OS (P = 0.072) in the early stage (Stage I & II) population, while in advanced patients, have prognostic value regardless of OS (P = 0.013) or DFS (P = 0.004) (Figs. 5E and 5F, Figs. 6E and 6F).