KEGG pathway analysis revealed their involvement in Yersinia infection, Leishmaniasis, and Pertussis (Fig. S1B), while Reactome pathways primarily included p75NTR recruitment of signaling complexes, NF-kB activation and survival signaling, and IRAK1 recruitment of the IKK complex (Fig. S1C). The gene discussed is NFKB1; the disease is Yersinia infectious disease.