Liu et al. found that treating AIH model mice with Bifidobacterium and Lactobacillus can significantly increase Treg cell infiltration, inhibit the production of Th1 and Th17 cells and inflammatory factors, and inhibit the activation of Toll-like receptor 4 (TLR4)/NF-κB pathway to alleviate the progression of AIH [83]. This evidence concerns the gene TLR4 and autoimmune hepatitis.