In nasopharyngeal carcinoma, miR-1278 exerts tumor-suppressive effects by targeting ATG28; miR-1278 expression is downregulated in colorectal carcinoma and tumor cell metastasis is inhibited by the targeting of CYP24A1, BTG2, and other downstream target genes [11,20]. This evidence concerns the gene CYP24A1 and colorectal carcinoma.