We found that AGTR1 A1166C (p = 0.01), AGT M235T (p = 0.01), AGT T174M (p = 0.02), hypertension (p = 0.03), smoking (p = 0.02), and family history of atherothrombotic disease (p = 0.04) were independently associated. The gene discussed is AGTR1; the disease is hypertensive disorder.