Low‐grade inflammation is a hallmark of hyperglycemia.(55) Although a variety of cytokines are affected by high glucose levels, we chose to focus on MCP‐1, which has been established as a regulator of glucose metabolism and insulin resistance,(56, 57) diabetic wound healing,(58) and as a potential genetic risk factor for T2DM (reviewed Panee(59)). This evidence concerns the gene CCL2 and Insulin resistance.